Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors

Tumor targeting by genetically modified mesenchymal stromal/stem cells (MSCs) carrying anti-cancer molecules represents a promising cell-based strategy. We previously showed that the pro-apoptotic agent tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can be successfully delivered by...

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Udgivet i:Cancer Gene Ther
Main Authors: Golinelli, Giulia, Grisendi, Giulia, Prapa, Malvina, Bestagno, Marco, Spano, Carlotta, Rossignoli, Filippo, Bambi, Franco, Sardi, Iacopo, Cellini, Monica, Horwitz, Edwin M., Feletti, Alberto, Pavesi, Giacomo, Dominici, Massimo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445885/
https://ncbi.nlm.nih.gov/pubmed/30464207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41417-018-0062-x
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