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Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition

Inflammation is an established risk factor for colorectal cancer. We and others have shown that colorectal cancer patients with elevated cysteinyl leukotriene receptor 2 (CysLT(2)R) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) levels exhibit good prognoses. However, both CysLT(2)R and 15-PGDH...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Satapathy, Shakti Ranjan, Topi, Geriolda, Osman, Janina, Hellman, Karin, Ek, Fredrik, Olsson, Roger, Sime, Wondossen, Mehdawi, Lubna M., Sjölander, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438320/
https://ncbi.nlm.nih.gov/pubmed/32814764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00256-0
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