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How to perform quantitative single cell proteomics with SCoPE2

The fate and physiology of individual cells are controlled by protein interactions. We recently developed SCoPE-MS, a method for direct analysis of proteomes of single cells by LC-MS/MS. SCoPE-MS is enabled by isobaric-tag multiplexing of peptides from single cells together with carrier material, wh...

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Detalles Bibliográficos
Publicado en:J Biomol Tech
Main Authors: Emmott, Edward, Huffman, R. Gray, Kharchenko, Peter, Koller, Antonius, Perlman, David H., Petelski, Aleksandra, Serra, Marco, Slavov, Nikolai, Specht, Harrison
Formato: Artigo
Idioma:Inglês
Publicado: Association of Biomolecular Resource Facilities 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424862/
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