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Overexpressed p32 localized in the endoplasmic reticulum and mitochondria negatively regulates calcium-dependent endothelial nitric oxide synthase activity

The p32 protein plays a crucial role in the regulation of cytosolic Ca(2+) concentrations ([Ca2+]c) that contributes to the Ca(2+)-dependent signaling cascade. Using an adenovirus and plasmid p32-overexpression system, the aim of the study was to evaluate the role of p32 in the regulation of [Ca(2+)...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Choi, Kwanhoon, Koo, Bon-Hyeock, Yoon, Byeong Jun, Jung, Minkyo, Yun, Hye Young, Jeon, Byung Hwa, Won, Moo-Ho, Kim, Young-Myeong, Mun, Ji Young, Lim, Hyun Kyo, Ryoo, Sungwoo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411372/
https://ncbi.nlm.nih.gov/pubmed/32705193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11307
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