Loading...
Design and Testing of Vector-Producing HEK293T Cells Bearing a Genomic Deletion of the SV40 T Antigen Coding Region
The use of the human embryonic kidney (HEK) 293T cell line to manufacture vectors for in vivo applications raises safety concerns due to the presence of SV40 T antigen-encoding sequences. We used CRISPR-Cas9 genome editing to remove the SV40 T antigen-encoding sequences from HEK293T cells by transfe...
Na minha lista:
| Udgivet i: | Mol Ther Methods Clin Dev |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Gene & Cell Therapy
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397404/ https://ncbi.nlm.nih.gov/pubmed/32775497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.07.006 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|