MST4 inhibits human hepatocellular carcinoma cell proliferation and induces cell cycle arrest via suppression of PI3K/AKT pathway

Objective: MST4 has exhibited functions in regulating cell polarity, Golgi apparatus, cell migration, and cancer. Mechanistically, it affects the activity of p-ERK, Hippo-YAP pathway and autophagy. The aim of this study is to further examine the functions of MST4 in hepatocellular carcinoma (HCC) an...

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Vydáno v:J Cancer
Hlavní autoři: Hao, Wei-Chao, Zhong, Qiu-Ling, Pang, Wen-Qian, Dian, Mei-Juan, Li, Jing, Han, Liu-Xin, Zhao, Wen-Tao, Zhang, Xiao-Ling, Xiao, Sheng-Jun, Xiao, Dong, Lin, Xiao-Lin, Jia, Jun-Shuang
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378920/
https://ncbi.nlm.nih.gov/pubmed/32742458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.45822
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