Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes

BACKGROUND: Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1 diabetes and early-to-moderate diabetic kidney disease. METH...

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發表在:N Engl J Med
Main Authors: Doria, A., Galecki, A.T., Spino, C., Pop-Busui, R., Cherney, D.Z., Lingvay, I., Parsa, A., Rossing, P., Sigal, R.J., Afkarian, M., Aronson, R., Caramori, M.L., Crandall, J.P., de Boer, I.H., Elliott, T.G., Goldfine, A.B., Haw, J.S., Hirsch, I.B., Karger, A.B., Maahs, D.M., McGill, J.B., Molitch, M.E., Perkins, B.A., Polsky, S., Pragnell, M., Robiner, W.N., Rosas, S.E., Senior, P., Tuttle, K.R., Umpierrez, G.E., Wallia, A., Weinstock, R.S., Wu, C., Mauer, M.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375708/
https://ncbi.nlm.nih.gov/pubmed/32579810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1916624
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