Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes

BACKGROUND: Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1 diabetes and early-to-moderate diabetic kidney disease. METH...

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Publicat a:N Engl J Med
Autors principals: Doria, A., Galecki, A.T., Spino, C., Pop-Busui, R., Cherney, D.Z., Lingvay, I., Parsa, A., Rossing, P., Sigal, R.J., Afkarian, M., Aronson, R., Caramori, M.L., Crandall, J.P., de Boer, I.H., Elliott, T.G., Goldfine, A.B., Haw, J.S., Hirsch, I.B., Karger, A.B., Maahs, D.M., McGill, J.B., Molitch, M.E., Perkins, B.A., Polsky, S., Pragnell, M., Robiner, W.N., Rosas, S.E., Senior, P., Tuttle, K.R., Umpierrez, G.E., Wallia, A., Weinstock, R.S., Wu, C., Mauer, M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375708/
https://ncbi.nlm.nih.gov/pubmed/32579810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1916624
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