CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV

CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCas12a has been developed for insect genome editing, and the novel Cas12a orthologs nucleases and editing efficiency require more study on i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Dong, Zhanqi, Qin, Qi, Hu, Zhigang, Zhang, Xinling, Miao, Jianghao, Huang, Liang, Chen, Peng, Lu, Cheng, Pan, Minhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373793/
https://ncbi.nlm.nih.gov/pubmed/32760714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00841
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