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Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context

Current immunohistochemical methods of studying microglia in the post-mortem human brain do not capture the heterogeneity of microglial function in response to damage and disease. We therefore investigated the expression of eight myeloid cell proteins associated with changes in function alongside Ib...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Swanson, Molly E. V., Murray, Helen C., Ryan, Brigid, Faull, Richard L. M., Dragunow, Mike, Curtis, Maurice A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366669/
https://ncbi.nlm.nih.gov/pubmed/32678124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68086-z
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