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Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole
Partial agonists of the dopamine D(2) receptor 18 (D(2)R) have been developed to treat the symptoms of schizophrenia without causing the side effects elicited by antagonists. The receptor–ligand interactions that determine the intrinsic efficacy of such drugs, however, are poorly understood. Aripipr...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7365685/ https://ncbi.nlm.nih.gov/pubmed/31339684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00342 |
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