Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy

BACKGROUND: Mitochondrial dysfunction contributes to the pathogenesis of diabetic nephropathy (DN). Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role in the transport of pyruvate into mitochondrial across the mitochondrial inner membrane. A pr...

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Publicado en:BMC Nephrol
Autores principales: Zhu, Huanhuan, Wan, Huiting, Wu, Lin, Li, Qing, Liu, Simeng, Duan, Suyan, Huang, Zhimin, Zhang, Chengning, Zhang, Bo, Xing, Changying, Yuan, Yanggang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362444/
https://ncbi.nlm.nih.gov/pubmed/32664896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-01931-5
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