Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production

One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles (SLNs) as gene delivery systems to induce the...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Vicente-Pascual, Mónica, Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Rodríguez-Gascón, Alicia, Muntoni, Elisabetta, Battaglia, Luigi, del Pozo-Rodríguez, Ana, Solinís Aspiazu, María Ángeles
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355708/
https://ncbi.nlm.nih.gov/pubmed/32586018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060584
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