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Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production

One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles (SLNs) as gene delivery systems to induce the...

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Publicado en:Pharmaceutics
Main Authors: Vicente-Pascual, Mónica, Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Rodríguez-Gascón, Alicia, Muntoni, Elisabetta, Battaglia, Luigi, del Pozo-Rodríguez, Ana, Solinís Aspiazu, María Ángeles
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355708/
https://ncbi.nlm.nih.gov/pubmed/32586018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060584
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