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Zearalenone-Induced Interaction between PXR and Sp1 Increases Binding of Sp1 to a Promoter Site of the eNOS, Decreasing Its Transcription and NO Production in BAECs

Zearalenone (ZEN) is a non-steroidal mycotoxin that has various toxicological impacts on mammalian health. Here, we found that ZEN significantly affected the production of nitric oxide (NO) and the expression of endothelial NO synthase (eNOS) of bovine aortic endothelial cells (BAECs). A promoter an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxins (Basel)
Päätekijät: Lee, Hyeon-Ju, Park, Jung-Hyun, Oh, Se-Young, Cho, Du-Hyong, Kim, Suji, Jo, Inho
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354576/
https://ncbi.nlm.nih.gov/pubmed/32630586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12060421
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