Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes

Hepatitis B virus (HBV) chronic infection is a critical risk factor for hepatocellular carcinoma. The innate immune response to HBV infection is a matter of debate. In particular, viral escape mechanisms are poorly understood. Our study reveals that HBV RNAs are not immunostimulatory in immunocompet...

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Vydáno v:Viruses
Hlavní autoři: Lauterbach-Rivière, Lise, Bergez, Maïwenn, Mönch, Saskia, Qu, Bingqian, Riess, Maximilian, Vondran, Florian W. R., Liese, Juliane, Hornung, Veit, Urban, Stephan, König, Renate
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354540/
https://ncbi.nlm.nih.gov/pubmed/32485908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12060592
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