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The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion

Some antihistamines have exhibited significant antitumor activity alone or in combination with other therapies in in vitro and clinical studies. However, the underlying mechanisms of how antihistamines inhibit hepatocellular carcinoma proliferation are still unknown. We first screened the antiprolif...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Liang, Yu-Chih, Chang, Chi-Ching, Sheu, Ming-Thau, Lin, Shyr-Yi, Chung, Chia-Chen, Teng, Chang-Ting, Suk, Fat-Moon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352610/
https://ncbi.nlm.nih.gov/pubmed/32570749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061610
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