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11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma

BACKGROUND: Understanding the status of intratumoural immune microenvironment is necessary to ensure the efficacy of immune-checkpoint (IC) blockade therapy. Cortisol plays pivotal roles in glucocorticoid interactions in the immune system. We examined the correlation between intratumourally synthesi...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Saito, Ryoko, Miki, Yasuhiro, Abe, Takuto, Miyauchi, Eisaku, Abe, Jiro, Nanamiya, Ren, Inoue, Chihiro, Sato, Ikuro, Sasano, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341889/
https://ncbi.nlm.nih.gov/pubmed/32336752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0837-3
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