Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor

BACKGROUND: The aim of this study was to test the feasibility and utility of developing patient-derived orthotopic xenograft (PDOX) models for patients with malignant peripheral nerve sheath tumors (MPNSTs) to aid therapeutic interventions in real time. PATIENT & METHODS: A sporadic relapsed MPN...

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Publicado en:Ther Adv Med Oncol
Main Authors: Fernández-Rodríguez, Juana, Morales La Madrid, Andrés, Gel, Bernat, Castañeda Heredia, Alicia, Salvador, Héctor, Martínez-Iniesta, María, Moutinho, Catia, Morata, Jordi, Heyn, Holger, Blanco, Ignacio, Creus-Bachiller, Edgar, Capella, Gabriel, Farré, Lourdes, Vidal, August, Soldado, Francisco, Krauel, Lucas, Suñol, Mariona, Serra, Eduard, Villanueva, Alberto, Lázaro, Conxi
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2020
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339074/
https://ncbi.nlm.nih.gov/pubmed/32670419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920929579
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