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Belimumab and Rituximab in Systemic Lupus Erythematosus: A Tale of Two B Cell-Targeting Agents

Given the centrality of B cells to systemic lupus erythematosus (SLE), it stands to reason that a candidate therapeutic agent that targets B cells could be efficacious. Both rituximab, a monoclonal antibody (mAb) that binds to CD20 on the surface of B cells, and belimumab, a mAb that binds and neutr...

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Detalles Bibliográficos
Publicado en:Front Med (Lausanne)
Main Authors: Wise, Leanna M., Stohl, William
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338653/
https://ncbi.nlm.nih.gov/pubmed/32695790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.00303
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