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LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation

Cilia and flagella are microtubule-based cellular projections with important sensory and motility functions. Their absence or malfunction is associated with a growing number of human diseases collectively referred to as ciliopathies. However, the fundamental mechanisms underpinning cilia biogenesis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Gonçalves, João, Sharma, Amit, Coyaud, Étienne, Laurent, Estelle M.N., Raught, Brian, Pelletier, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337498/
https://ncbi.nlm.nih.gov/pubmed/32496561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201908132
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