The chromatin remodeler SRCAP promotes self‐renewal of intestinal stem cells

Lgr5(+) intestinal stem cells (ISCs) exhibit self‐renewal and differentiation features under homeostatic conditions, but the mechanisms controlling Lgr5 + ISC self‐renewal remain elusive. Here, we show that the chromatin remodeler SRCAP is highly expressed in mouse intestinal epithelium and ISCs. Sr...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Ye, Buqing, Yang, Liuliu, Qian, Guomin, Liu, Benyu, Zhu, Xiaoxiao, Zhu, Pingping, Ma, Jing, Xie, Wei, Li, Huimu, Lu, Tianku, Wang, Yanying, Wang, Shuo, Du, Ying, Wang, Zhimin, Jiang, Jing, Li, Jinsong, Fan, Dongdong, Meng, Shu, Wu, Jiayi, Tian, Yong, Fan, Zusen
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327502/
https://ncbi.nlm.nih.gov/pubmed/32449550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103786
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