Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia

We previously demonstrated that hexokinase II (HK2) dissociation from mitochondria during cardiac ischemia correlates with cytochrome c (cyt-c) loss, oxidative stress and subsequent reperfusion injury. However, whether HK2 release is the primary signal mediating this ischemia-induced mitochondrial d...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Pereira, Gonçalo C., Lee, Laura, Rawlings, Nadiia, Ouwendijk, Joke, Parker, Joanne E., Andrienko, Tatyana N., Henley, Jeremy M., Halestrap, Andrew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7313731/
https://ncbi.nlm.nih.gov/pubmed/32579577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234653
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky