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TDO Promotes Hepatocellular Carcinoma Progression

PURPOSE: Tryptophan 2,3-dioxygenase (TDO), encoded by the gene TDO2, is an enzyme that catalyses the first and rate-limiting step of tryptophan (Try) degradation in the kynurenine (Kyn) pathway in the liver. Recently, TDO has been demonstrated to be expressed in various human tumours, especially hep...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Li, Shanbao, Li, Lei, Wu, Junyi, Song, Fangbin, Qin, Zhiwei, Hou, Lei, Xiao, Chao, Weng, Junyong, Qin, Xuebin, Xu, Junming
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311207/
https://ncbi.nlm.nih.gov/pubmed/32606795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S252929
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