Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3′UTR intron-containing NMD targets

Many post-transcriptional mechanisms operate via mRNA 3′UTRs to regulate protein expression, and such controls are crucial for development. We show that homozygous mutations in two zebrafish exon junction complex (EJC) core genes rbm8a and magoh leads to muscle disorganization, neural cell death, an...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Gangras, Pooja, Gallagher, Thomas L., Parthun, Michael A., Yi, Zhongxia, Patton, Robert D., Tietz, Kiel T., Deans, Natalie C., Bundschuh, Ralf, Amacher, Sharon L., Singh, Guramrit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310861/
https://ncbi.nlm.nih.gov/pubmed/32502192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008830
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