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The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs
Calcipressin-1, also known as regulator of calcineurin 1 (RCAN1), can specifically bind calcineurin at or near the calcineurin A catalytic domain and downregulate calcineurin activity. However, whether RCAN1 affects the hypoxic intervertebral disc (IVD) phenotype through the calcineurin/NFAT signali...
Gespeichert in:
Veröffentlicht in: | Exp Mol Med |
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Hauptverfasser: | , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Nature Publishing Group UK
2020
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272636/ https://ncbi.nlm.nih.gov/pubmed/32467610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0441-x |
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