Population Pharmacokinetics and Dosage Optimization of Linezolid in Patients with Liver Dysfunction

Linezolid is the first synthetic oxazolidone agent to treat infections caused by Gram-positive pathogens. Infected patients with liver dysfunction (LD) are more likely to suffer from adverse reactions, such as thrombocytopenia, when standard-dose linezolid is used than patients with LD who did not u...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Zhang, Su-hua, Zhu, Zhen-yu, Chen, Zi, Li, Ying, Zou, Yang, Yan, Miao, Xu, Yun, Wang, Feng, Liu, Mou-ze, Zhang, Min, Zhang, Bi-kui
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269467/
https://ncbi.nlm.nih.gov/pubmed/32253210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00133-20
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