The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue

BACKGROUND: It is well known that androgen-deprivation therapy (ADT) can inevitably drive prostate cancer (PCa) cells into a castration-resistant state. According to the “Warburg effect”, the metabolism of aggressive tumor cells increases significantly. The growth of cancer cells depends on glycolys...

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發表在:BMC Urol
Main Authors: Li, Ximing, Chen, Zhi, Li, Zuan, Huang, Guihai, Lin, Junhao, Wei, Qiang, Liang, Jianbo, Li, Wei
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268689/
https://ncbi.nlm.nih.gov/pubmed/32487245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-020-00635-0
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