Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway

BACKGROUND: Growth arrest-specific 6 (GAS6) is a secreted vitamin K-dependent protein abnormally expressed in various human tumor tissues and can activate the receptor Tyro3, Axl, and Mer to promote cancer cell proliferation and invasion. Until now, the role of GAS6 has been poorly understood in bla...

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Pubblicato in:Onco Targets Ther
Autori principali: Mao, Shiyu, Wu, Yuan, Wang, Ruiliang, Guo, Yadong, Bi, Dexi, Ma, Wenchao, Zhang, Wentao, Zhang, Junfeng, Yan, Yang, Yao, Xudong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261663/
https://ncbi.nlm.nih.gov/pubmed/32547108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S237174
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