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Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway

BACKGROUND: Growth arrest-specific 6 (GAS6) is a secreted vitamin K-dependent protein abnormally expressed in various human tumor tissues and can activate the receptor Tyro3, Axl, and Mer to promote cancer cell proliferation and invasion. Until now, the role of GAS6 has been poorly understood in bla...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Mao, Shiyu, Wu, Yuan, Wang, Ruiliang, Guo, Yadong, Bi, Dexi, Ma, Wenchao, Zhang, Wentao, Zhang, Junfeng, Yan, Yang, Yao, Xudong
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261663/
https://ncbi.nlm.nih.gov/pubmed/32547108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S237174
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