The RNA disruption assay is superior to conventional drug sensitivity assays in detecting cytotoxic drugs

Conventional drug sensitivity assays used to screen prospective anti-cancer agents for cytotoxicity monitor biological processes associated with active growth and proliferation, used as proxies of cell viability. However, these assays are unable to distinguish between growth-arrested (but otherwise...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Mapletoft, Jonathan P. J., St-Onge, Renée J., Guo, Baoqing, Butler, Phillipe, Masilamani, Twinkle J., D’costa, Lavina, Pritzker, Laura B., Parissenti, Amadeo M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250890/
https://ncbi.nlm.nih.gov/pubmed/32457334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65579-9
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