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Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice
BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis and characterized by degeneration of the articular cartilage. Mitogen-inducible gene 6 (Mig-6) has been identified as a negative regulator of the epidermal growth factor receptor (EGFR). Cartilage-specific Mig-6 knockout (KO) mice...
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| Publicado no: | Arthritis Res Ther |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236969/ https://ncbi.nlm.nih.gov/pubmed/32430054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02213-z |
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