Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn’s Disease Patients

Crohn’s disease (CD) is a multifactorial incurable chronic disorder. Current medical treatment seeks to induce and maintain a state of remission. During episodes of inflammation, monocytes infiltrate the inflamed mucosa whereupon they differentiate into macrophages with a pro-inflammatory phenotype....

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Li Yim, Andrew Y.F., Duijvis, Nicolette W., Ghiboub, Mohammed, Sharp, Catriona, Ferrero, Enrico, Mannens, Marcel M.A.M., D’Haens, Geert R., de Jonge, Wouter J., te Velde, Anje A., Henneman, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230341/
https://ncbi.nlm.nih.gov/pubmed/32276386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9041055
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