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Trefoil factors share a lectin activity that defines their role in mucus

The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell migration, though the molecular mechanisms underlying these functions have remained poorly defined. Here, we demons...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Järvå, Michael A., Lingford, James P., John, Alan, Soler, Niccolay Madiedo, Scott, Nichollas E., Goddard-Borger, Ethan D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221086/
https://ncbi.nlm.nih.gov/pubmed/32404934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16223-7
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