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PLCE1 regulates the migration, proliferation, and differentiation of podocytes

PLCE1 encodes phospholipase C epsilon, and its mutations cause recessive nephrotic syndrome. However, the mechanisms by which PLCE1 mutations result in defects associated with glomerular function are not clear. To address this, we investigated the function of PLCE1 in podocytes called glomerular epi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Mol Med
Hauptverfasser: Yu, Seyoung, Choi, Won-Il, Choi, Yo Jun, Kim, Hye-Youn, Hildebrandt, Friedhelm, Gee, Heon Yung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210307/
https://ncbi.nlm.nih.gov/pubmed/32238860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0410-4
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