3D ATAC-PALM: Super-resolution Imaging of the Accessible Genome

To image the accessible genome at nanometer scale in situ, we developed 3D ATAC-PALM which integrates Assay for Transposase-Accessible Chromatin with visualization, PALM super-resolution imaging and lattice light-sheet microscopy. Multiplexed with Oligopaint DNA-FISH, RNA-FISH and protein fluorescen...

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Publicat a:Nat Methods
Autors principals: Xie, Liangqi, Dong, Peng, Chen, Xingqi, Hsieh, Tsung-Han S., Banala, Sambashiva, De Marzio, Margherita, English, Brian P., Qi, Yifeng, Jung, Seol Kyoung, Kieffer-Kwon, Kyong-Rim, Legant, Wesley R., Hansen, Anders S., Schulmann, Anton, Casellas, Rafael, Zhang, Bin, Betzig, Eric, Lavis, Luke D., Chang, Howard Y., Tjian, Robert, Liu, Zhe
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207063/
https://ncbi.nlm.nih.gov/pubmed/32203384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0775-2
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