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RAF kinases are stabilized and required for dendritic cell differentiation and function

RAF kinases (ARAF, BRAF, and CRAF) are highly conserved enzymes that trigger the RAF-MEK1/2-ERK1/2 (MAPK) pathway upon activation of RAS. Despite enormous clinical interest, relatively little is known on the role of RAFs in mediating immune responses. Here, we investigated the role of RAF kinases an...

詳細記述

保存先:
書誌詳細
出版年:Cell Death Differ
主要な著者: Riegel, Kristina, Schlöder, Janine, Sobczak, Marco, Jonuleit, Helmut, Thiede, Bernd, Schild, Hansjörg, Rajalingam, Krishnaraj
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206131/
https://ncbi.nlm.nih.gov/pubmed/31541179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0416-4
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