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RAF kinases are stabilized and required for dendritic cell differentiation and function
RAF kinases (ARAF, BRAF, and CRAF) are highly conserved enzymes that trigger the RAF-MEK1/2-ERK1/2 (MAPK) pathway upon activation of RAS. Despite enormous clinical interest, relatively little is known on the role of RAFs in mediating immune responses. Here, we investigated the role of RAF kinases an...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206131/ https://ncbi.nlm.nih.gov/pubmed/31541179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0416-4 |
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