Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze

Abnormal wound repair has been observed in the airway epithelium of patients with chronic respiratory diseases, including asthma. Therapies focusing on repairing vulnerable airways, particularly in early life, present a potentially novel treatment strategy. We report defective lower airway epithelia...

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Publicado en:JCI Insight
Autores principales: Iosifidis, Thomas, Sutanto, Erika N., Buckley, Alysia G., Coleman, Laura, Gill, Erin E., Lee, Amy H., Ling, Kak-Ming, Hillas, Jessica, Looi, Kevin, Garratt, Luke W., Martinovich, Kelly M., Shaw, Nicole C., Montgomery, Samuel T., Kicic-Starcevich, Elizabeth, Karpievitch, Yuliya V., Le Souëf, Peter, Laing, Ingrid A., Vijayasekaran, Shyan, Lannigan, Francis J., Rigby, Paul J., Hancock, Robert E.W., Knight, Darryl A., Stick, Stephen M., Kicic., Anthony
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205257/
https://ncbi.nlm.nih.gov/pubmed/32208383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133125
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