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Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze

Abnormal wound repair has been observed in the airway epithelium of patients with chronic respiratory diseases, including asthma. Therapies focusing on repairing vulnerable airways, particularly in early life, present a potentially novel treatment strategy. We report defective lower airway epithelia...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Iosifidis, Thomas, Sutanto, Erika N., Buckley, Alysia G., Coleman, Laura, Gill, Erin E., Lee, Amy H., Ling, Kak-Ming, Hillas, Jessica, Looi, Kevin, Garratt, Luke W., Martinovich, Kelly M., Shaw, Nicole C., Montgomery, Samuel T., Kicic-Starcevich, Elizabeth, Karpievitch, Yuliya V., Le Souëf, Peter, Laing, Ingrid A., Vijayasekaran, Shyan, Lannigan, Francis J., Rigby, Paul J., Hancock, Robert E.W., Knight, Darryl A., Stick, Stephen M., Kicic., Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205257/
https://ncbi.nlm.nih.gov/pubmed/32208383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133125
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