Molecular Hybrids Integrated with Benzimidazole and Pyrazole Structural Motifs: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

[Image: see text] Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a–6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a hybrid-possessing para-nitrophenyl moiety connected to a pyrazole scaffold (6a) exerted the highest anti-inf...

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Foilsithe in:ACS Omega
Main Authors: Sivaramakarthikeyan, Ramar, Iniyaval, Shunmugam, Saravanan, Vadivel, Lim, Wei-Meng, Mai, Chun-Wai, Ramalingan, Chennan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203960/
https://ncbi.nlm.nih.gov/pubmed/32391496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00630
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