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Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer

Metastasis, the leading cause of death in cancer patients, requires the invasion of tumor cells through the stroma in response to migratory cues, in part provided by the extracellular matrix (ECM). Recent advances in proteomics have led to the identification of hundreds of ECM proteins, which are mo...

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Dettagli Bibliografici
Pubblicato in:APL Bioeng
Autori principali: Baskaran, Janani P., Weldy, Anna, Guarin, Justinne, Munoz, Gabrielle, Shpilker, Polina H., Kotlik, Michael, Subbiah, Nandita, Wishart, Andrew, Peng, Yifan, Miller, Miles A., Cowen, Lenore, Oudin, Madeleine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: AIP Publishing LLC 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202897/
https://ncbi.nlm.nih.gov/pubmed/32455252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5143779
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