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Effects of CYP3A5 Polymorphisms on Efficacy and Safety of Tacrolimus Therapy in Patients with Idiopathic Membranous Nephropathy

BACKGROUND: Tacrolimus (TAC) is beneficial for patients with idiopathic membranous nephropathy (IMN). It has a narrow therapeutic concentration range and many factors influence TAC blood concentration. CYP3A5 is the most important enzyme in TAC metabolism. The aim of this study was to analyze the ef...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmgenomics Pers Med
Hauptverfasser: Zhang, Chengning, Duan, Suyan, Guo, Miao, Yuan, Yanggang, Huang, Zhimin, Zhu, Jingfeng, Sun, Bin, Zhang, Bo, Xing, Changying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186213/
https://ncbi.nlm.nih.gov/pubmed/32368128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S247892
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