Biologically driven cut-off definition of lymphocyte ratios in metastatic breast cancer and association with exosomal subpopulations and prognosis

High neutrophil to lymphocyte ratio (NLR) and monocyte to lymphocyte ratio (MLR) are respectively associated with systemic inflammation and immune suppression and have been associated with a poor outcome. Plasmatic exosomes are extracellular vesicles involved in the intercellular communication syste...

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Udgivet i:Sci Rep
Main Authors: Gerratana, Lorenzo, Basile, Debora, Toffoletto, Barbara, Bulfoni, Michela, Zago, Silvia, Magini, Alessandro, Lera, Marta, Pelizzari, Giacomo, Parisse, Pietro, Casalis, Loredana, Vitale, Maria Grazia, Fanotto, Valentina, Bonotto, Marta, Caponnetto, Federica, Bartoletti, Michele, Lisanti, Camilla, Minisini, Alessandro Marco, Emiliani, Carla, Di Loreto, Carla, Fasola, Gianpiero, Curcio, Francesco, Beltrami, Antonio Paolo, Cesselli, Daniela, Puglisi, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181663/
https://ncbi.nlm.nih.gov/pubmed/32332763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63291-2
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