Biologically driven cut-off definition of lymphocyte ratios in metastatic breast cancer and association with exosomal subpopulations and prognosis

High neutrophil to lymphocyte ratio (NLR) and monocyte to lymphocyte ratio (MLR) are respectively associated with systemic inflammation and immune suppression and have been associated with a poor outcome. Plasmatic exosomes are extracellular vesicles involved in the intercellular communication syste...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gerratana, Lorenzo, Basile, Debora, Toffoletto, Barbara, Bulfoni, Michela, Zago, Silvia, Magini, Alessandro, Lera, Marta, Pelizzari, Giacomo, Parisse, Pietro, Casalis, Loredana, Vitale, Maria Grazia, Fanotto, Valentina, Bonotto, Marta, Caponnetto, Federica, Bartoletti, Michele, Lisanti, Camilla, Minisini, Alessandro Marco, Emiliani, Carla, Di Loreto, Carla, Fasola, Gianpiero, Curcio, Francesco, Beltrami, Antonio Paolo, Cesselli, Daniela, Puglisi, Fabio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181663/
https://ncbi.nlm.nih.gov/pubmed/32332763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63291-2
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