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Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction

Glyceraldehyde-derived advanced glycation end products (glycer-AGEs) contribute to proximal tubulopathy in diabetes. However, what glycer-AGE structure could evoke tubular cell damage remains unknown. We first examined if deleterious effects of glycer-AGEs on reactive oxygen species (ROS) generation...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sotokawauchi, Ami, Nakamura, Nobutaka, Matsui, Takanori, Higashimoto, Yuichiro, Yamagishi, Sho-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177832/
https://ncbi.nlm.nih.gov/pubmed/32283652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072604
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