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Inactivation of interleukin‐8 by aminopeptidase N (CD13)

Aminopeptidase (APN) was found to degrade interleukin‐8 (IL‐8) and inactivate its chemotactic activity. The chemotactic activity of IL‐8 was decreased by APN or neutrophil plasma membranes dose‐ and time‐dependently. The chemotactic activity was not inactivated in the presence of bestatin or WM15 mo...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Kanayama, Naohiro, Kajiwara, Yayoi, Goto, Junko, Maradny, Emad EL, Maehara, Kayoko, Andou, Katuaki, Terao, Toshihiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166322/
https://ncbi.nlm.nih.gov/pubmed/7829964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlb.57.1.129
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