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Inactivation of interleukin‐8 by aminopeptidase N (CD13)

Aminopeptidase (APN) was found to degrade interleukin‐8 (IL‐8) and inactivate its chemotactic activity. The chemotactic activity of IL‐8 was decreased by APN or neutrophil plasma membranes dose‐ and time‐dependently. The chemotactic activity was not inactivated in the presence of bestatin or WM15 mo...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Kanayama, Naohiro, Kajiwara, Yayoi, Goto, Junko, Maradny, Emad EL, Maehara, Kayoko, Andou, Katuaki, Terao, Toshihiko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166322/
https://ncbi.nlm.nih.gov/pubmed/7829964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlb.57.1.129
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