Inactivation of interleukin‐8 by aminopeptidase N (CD13)

Aminopeptidase (APN) was found to degrade interleukin‐8 (IL‐8) and inactivate its chemotactic activity. The chemotactic activity of IL‐8 was decreased by APN or neutrophil plasma membranes dose‐ and time‐dependently. The chemotactic activity was not inactivated in the presence of bestatin or WM15 mo...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Kanayama, Naohiro, Kajiwara, Yayoi, Goto, Junko, Maradny, Emad EL, Maehara, Kayoko, Andou, Katuaki, Terao, Toshihiko
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 1995
Fag:
Journal Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166322/
https://ncbi.nlm.nih.gov/pubmed/7829964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlb.57.1.129
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