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Budding Yeast SKP1 Encodes an Evolutionarily Conserved Kinetochore Protein Required for Cell Cycle Progression

The budding yeast SKP1gene, identified as a dosage suppressor of a known kinetochore protein mutant, encodes an intrinsic 22.3 kDa subunit of CBF3, a multiprotein complex that binds centromere DNA in vitro. Temperature-sensitive mutations in SKP1 define two distinct phenotypic classes. skp1-4 mutant...

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Udgivet i:Cell
Main Authors: Connelly, Carla, Hieter, Philip
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press. 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125826/
https://ncbi.nlm.nih.gov/pubmed/8706132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0092-8674(00)80099-9
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