Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups

Histiocytic sarcoma is a rare malignant neoplasm that may occur de novo or in the context of a previous hematologic malignancy or mediastinal germ cell tumor. Here, we performed whole exome sequencing and RNA-sequencing (RNA-Seq) on 21 archival cases of primary histiocytic sarcoma. We identified a h...

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Publicado en:Haematologica
Main Authors: Egan, Caoimhe, Nicolae, Alina, Lack, Justin, Chung, Hye-Jung, Skarshaug, Shannon, Pham, Thu Anh, Navarro, Winnifred, Abdullaev, Zied, Aguilera, Nadine S., Xi, Liqiang, Pack, Svetlana, Pittaluga, Stefania, Jaffe, Elaine S., Raffeld, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109753/
https://ncbi.nlm.nih.gov/pubmed/31439678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.230375
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