Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM

T1DM (type 1 diabetes mellitus), which results from the irreversible elimination of beta-cells mediated by autoreactive T cells, is defined as an autoimmune disease. It is widely accepted that T1DM is caused by a combination of genetic and environmental factors, but the precise underlying molecular...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Pang, Haipeng, Luo, Shuoming, Huang, Gan, Xia, Ying, Xie, Zhiguo, Zhou, Zhiguang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080653/
https://ncbi.nlm.nih.gov/pubmed/32226409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00119
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